Students have access to all of the major statistical software packages (BMD-P, SPSS, SPSS-X, MINI-TABS, etc.) through one of the computer labs (IBM-compatible) that are located on campus (including one in the Owings-McQuagge building). Macintosh computers are available in the lab that is located in the Performing Arts Center. Computers are linked to the internet, and iTech provides accounts for the entire Southern Miss community, including graduate students. Students thus have access to free, unlimited internet services and personal e-mail accounts.

Library functions at The University of Southern Mississippi are organized into four major units: the Joseph Cook Memorial Library (located directly across the street from Owings-McQuagge Hall), the William David McCain Library and Archives, the Teaching Learning Resources Center , and the Cox Library at the Gulf Coast campus. The Cook Library has recently undergone a major construction expansion and currently acquisitions over 20,000 new volumes annually. The holdings of the Library include more than 1.8 million volumes of books, bound journals, government documents and microfilms. The Library also subscribes to more than 4,732 periodicals, and cataloging services are available by computer throughout the campus. Access to dozens of on-line databases is provided through the reference department and a variety of CD/ROM index services are available on site free of charge. Recently, Southern Miss added an on-line connection with a library service that has major journal holdings. If needed journal articles are not available on campus, a faxed copy may be obtained from the on-line service at no cost to faculty members or graduate students.