University of South CarolinaM.S. 2000-2002Marine
Science
University of South CarolinaC.A.S2003-2005 Statistics
University of South CarolinaPh.D.2002-2006 Environ.
Health Sciences
University of FloridaPost-doc2006-2008 Nanotoxicology
Research Interests:
The main interest of my laboratory centers around the study of the effect of anthropogenic contaminant on aquatic organisms. We focus on molecular approaches, aimed at identifying the precise cellular and molecular pathways that are affected by different contaminants. Specific research projects address:
the effects of nanoparticulate metals on marine and freshwater fish
Application of molecular tools for assesment of ecosystem health
Isolation and characterization of miRNA expression patterns in non-model species
Professional Affiliations:
Society of Environmental Chemistry and Toxicology (SETAC)
Society of Toxicology
Publications: Griffitt,
RJ, K. Hyndman, ND Denslow, DS Barber.2009.Comparison
of molecular and histological changes in zebrafish gills exposed to metallic nanoparticles.Tox.
Sci. 107(2) 404-415.
Garcia-Reyero#,
N, Griffitt#, RJ, L Liu, KJ Kroll, WG Farmerie, DS Barber, and ND
Denslow.2008.Construction of a robust microarray from a non-model species (Largemouth
Bass) using pyrosequencing technology.Journal of Fish
Biology72, 2354-2376. # denotes shared first
authorship
Griffitt,
RJ, J Liu, J Gao, CW Bonzango, and DS Barber.2008.Acute toxicity of metallic
nanoparticles to aquaticorganisms.Environ.
Toxicol. Chem. 27(9), 1972-1978.
Griffitt, RJ, RW Weil, K. Hyndman, K Powers,
ND Denslow, and DS Barber.2007.Exposure to copper nanoparticles induce gill injury and acute
lethality in zebrafish (Danio rerio).Environ. Sci. and Toxicol.
41, 8178-8196.
Griffitt, RJ, TL Greig, GT Chandler, and JM
Quattro.2007.Serial Analysis of Gene Expression (SAGE)
reveals identifiable patterns in
transcriptome profiles of Palaemonetes
pugio exposed to three common environmental stressors.Environ.
Toxicol. and Chem.26(11),
2413-2419.
Griffitt,
RJ, GT Chandler, T.W. Greig, and JM Quattro.2006.Cathepsin B and Glutathione
Peroxidase show differing transcriptional responses in the grass
shrimp, Palaemonetes pugio following
exposure to three xenobiotics.Environ. Sci. and Toxicol.40, 3640-3645.
Staton
JL, Schizas NV, Klosterhaus SL, Griffitt RJ, Chandler
GT, CoullBC.2002. Effect of salinity variation and
pesticide exposure on an estuarine harpacticoid
copepod, Microarthridion littorale (Poppe 1881), in the southeastern US.
Journal of Experimental Marine Biology and Ecology278(2):
99-108.
Griffitt,
J, M Posey, and T Alphin. 1999.Effects
of edge fragmentation on oyster reef utilization by transient nekton. Journal
of the Elisha Mitchell Scientific Society99(2).
98-102.
Patents/Licenses:
License
to EcoArray --13,000 largemouth bass
genes for microarray analysis,Nancy
Denslow, David Barber, Robert J Griffitt, and Natalia Garcia-Reyero. June 2007.
Research Support:
Determination of effects of long-term exposure to sublethal
concentrations of metallic nanomaterials on zebrafish. $73,190.Subaward from University of Florida from NSF grant number XXXX.2009-2011.