Back Row (L to R):
Arthur LeBlanc, Wei Guo, Jared Cobb, William Adkins
Row: Eric Gorder, Ryan Hensarling, Bradley Sparks, Derek Patton,
Front Row (L to R): Yidan Guan, LaTonya
Hayes, Li Xiong, Emily Hoff, Matthew Jungman
Austin Baranek, Ethan Hoff, Katie Davis, Laken Kendrick
Welcome to the home page of the
Patton Research Group!!
Research in the Patton Group is centered on the design of new polymeric materials. We are particularly interested in the
design of functional polymer surfaces and thin films with
applications ranging from antifouling coatings to fuel cell
membranes. Our work environment is team-oriented and
interdisciplinary bringing together scientists with expertise in
polymer synthesis, surface chemistry, thin film fabrication, and surface analytical
techniques for the design of functional polymer surfaces.
Thiol-Isocyanate "click" reactions: Rapid development of
functional polymeric surfaces
communication published in Polymer Chemistry was featured as a
"Hot Article" and on the Inside Front Cover of the first issue
in 2011. The paper describes the use of thiol-isocyanate
chemistry as a modular platform for rapid and robust fabrication
of highly functional, multicomponent surfaces.
Further Reading: Hensarling,
R.; Rahane, S.; LeBlanc, A.; Sparks, B.; White, E.; Locklin,
J.; Patton, D.
“Click” Reactions: Rapid Development of Functional Polymeric
2011, 2, 88-90.
Surfaces with Sunlight
the chemistry and topography of surfaces affords technological
advancements for a variety of applications ranging
from biosensors to microelectronics. In this work, graduate
student Ryan Hensarling and coworkers demonstrated thiol-yne
click chemistry as a modular platform for rapid fabrication of
highly functional, patterned, and multicomponent surfaces.
The radical-mediated reaction of a thiol with an alkyne
generates a dithioether adduct in near quantitative yields under
ambient air, temperature, and humidity conditions. Here,
brush surfaces expressing a three-dimensional configuration of
“yne” functionalities were modified with high efficiency and
short reaction times (several minutes) using a library of
commercially available thiols, including functional thiols that
demonstrate applicability for pH responsive surfaces and for
bioconjugation. Patterned and multicomponent brush
surfaces were obtained using a simple UV photopatterning
technique and sequential thiol-yne reactions. Since thiyl
radicals can be generated using visible light, surfaces were
modified with thiol-yne click reactions outdoors using sunlight
as the radiation source. These results suggest the
possibility of large scale surface modifications using renewable
reading: Hensarling, R.; Doughty, V.; Chan, J.; Patton, D.
"Clicking Polymer Brushes with Thiol-Yne Chemistry: Inside and
J. Am. Chem. Soc. 2009, 131, 14673-14675.