Charles L. McCormick

Professor of Polymer Science
School of Polymers and High Performance Materials
Polymer Science Building,Room 314
118 College Drive #10076
Hattiesburg,MS 39406-0001
Phone:(601)-266-4872
Fax:(601)-266-5504
Email: Charles.McCormick@usm.edu
Research Group Web Page

Background

BS, Chemistry, Millsaps College , 1968. PhD, Chemistry, University of Florida , 1973. Senior Research Chemist, AKZO, 1973-74. Visiting Professor Cambridge University , 1992. Royal Institute of Sweden , 1997. Department of Polymer Science, The University of Southern Mississippi, 1974-present. Professor, 1981-present. Bennett Distinguished Professor of Science, 1997-1999.

Research Areas

Controlled free radical polymerization via aqueous RAFT, Rational design of polymer architecture for nanomedicine, Self-assembly of stimuli-responsive block copolymers, Conjugation and delivery of diagnostic and therapeutic agents, In Situ formation of polymer-stabilized nanoparticles, Associative hydrogel networks for biomedical applications, Targeted cellular delivery of siRNA/polyelectrolyte nanoparticles

Representative Publications

Adam W. York, Yilin Zhang, Andrew C. Holley, Yanlin Guo, Faqing Huang and Charles L. McCormick, “Facile Synthesis of Multivalent Folate-Block Copolymer Conjugates via Aqueous RAFT Polymerization: Targeted Delivery of siRNA and Subsequent Gene Suppression,”  Biomacromolecules, 2009,10(4), 936-943

Adam E. Smith, Xuewei Xu, Thomas U. Abell, Stacey E. Kirkland, Ryan M. Hensarling and Charles L. McCormick, “Tuning Nanostructure Morphology and Gold Nanoparticle “Locking” of Multiply-Responsive Amphiphilic Diblock Copolymers,” Macromolecules, 2009, 42(8), 2958-2964

Joel D. Flores, Xuewei Xu, Nicolas J. Treat and Charles L. McCormick, “Reversible “Self-Locked” Micelles from a Zwitterion-Containing Triblock Copolymer,” Macromolecules, 2009, 4(14), 4941–4945

Atsushi Sogabe and Charles L. McCormick, “Reversible Addition-Fragmentation Chain Transfer (RAFT) Polymerization in an Inverse Microemulsion System: Homopolymerizaton and Chain Extension,” Macromolecules, 2009, 42(14), 5043–5052

Brent S. Sumerlin, Brad S. Lokitz, Jonathan E. Stempka, Charles L. McCormick, “RAFT-Synthesized Diblock and Triblock Copolymers: Thermally-Induced Supramolecular Assembly in Aqueous Media,” Soft Matter, 2008, 4, 1760-1773

Adam W. York, Stacey E. Kirkland, Charles L. McCormick, “Advances in the Synthesis of Amphiphilic Block Copolymers via RAFT Polymerization: Stimuli-Responsive Drug and Gene Delivery,” Advanced Drug Delivery Review, 2008, 60(9), 1018-1036

Stacey E. Kirkland, Ryan M. Hensarling, Shawn D. McConaughy, William L. Jarrett and Charles L. McCormick, “Thermoreversible Hydrogels from RAFT-Synthesized BAB Triblock Copolymers: Steps Toward Biomimetic Matrices for Tissue Regeneration,” Biomacromolecules, 2008, 9, 472-480

Yuting Li, Adam E. Smith, Brad S. Lokitz, and Charles L. McCormick, “In Situ Formation of Gold -“Decorated” Vesicles from a RAFT-Synthesized, Thermally Responsive Block Copolymer,” Macromolecules, 2007, 40(24), 8524-8526

Adam W. York Charles W. Scales, Faqing Huang, Charles L. McCormick, “Facile Synthetic Procedure for w, Primary Amine Functionalization Directly in Water for Subsequent Fluorescent Labeling and Potential Bioconjugation of RAFT Synthesized (Co)Polymers,” Biomacromolecules, 8(8), 2007, 2337-2341

Sarah E. Morgan, Paul  Jones, Andrew S. Lamont, Andrew Heidenreich and Charles L. McCormick, “pH-Dependent Layer-by-Layer Assembly of Polyelectrolyte Homo-andBlock (Co)Polymers with Controlled Structures Synthesized via RAFT,” Langmuir, 2007, 23, 230-240

Andrew B. Lowe and Charles L. McCormick, “Reversible Addition-Fragmentation Chain Transfer (RAFT) Radical Polymerization and the Synthesis of Water-Soluble (Co)Polymers in Homogeneous Organic and Aqueous Media,” Progress in Polymer Science 32, 2007,283-351

Yuting Li, Brad S. Lokitz, and Charles L. McCormick, “Thermally Responsive Vesicles and Their Structural “Locking” via Polyelectrolyte Complex Formation,” Angewandte Chemie, 2006, 118(35) 5924-5927

C.L. McCormick and A.B. Lowe,“Recent Developments in Synthesis of Functional Water-Soluble Copolymers with Controlled Structures,” Accounts of Chemical Research 37, 2004, 312-325

A.B. Lowe and C.L. McCormick, “Synthesis and Solution Properties of Zwitterionic (Co)Polymers,” Chemical Reviews, 2002, 102[11], 4177-4190