Vijay Rangachari, Ph.D.

In a broad sense, my lab is interested in protein-protein, and protein-ligand interactions as well as molecular recognition. Specifically, we are interested in delineating the underlying molecular mechanisms that dictate protein aggregation and amyloid formation. In addition, my lab is involved in developing structure-based design of 'conformation-specific' molecules that are directed towards recognizing pathogenic 'cross-beta sheet' polypeptide structures.

Our quest to unravel the molecular mechanisms involved in amyloid diseases is not confined to our field of expertise. We strongly believe that inter-disciplinary approach is imperative to translate molecular theories into meaningful therapies. Therefore, we collaborate with several research groups.