Dr. Fengwei Bai
Professor
Bio
Dr. Bai received his Ph.D. in Genetics from Fudan University and did his postdoctoral training at Yale University School of Medicine. Dr. Bai's research interests are to understand how viruses are recognized by the host’s innate immune system and how innate immunity initiates and generates protective adaptive immunity. His long-term research goal is to use this knowledge in the rational design of effective vaccines or therapeutics for the prevention of the transmission of viral pathogens. Dr. Bai’s research is funded by NIH and various research foundations. For a detailed publication list, please visit: https://www.ncbi.nlm.nih.gov/myncbi/fengwei.bai.1/bibliography/public/ Dr. Bai is managing the USDA-certified Biosafety-Level 3 (BSL3) cell culture and animal research facilities, and collaborations from academia and industry are welcome!
- PHD - Fudan University (2002)
- MS - Ocean University of China (1999)
BSC486/586 Immunology
BSC484/584 Virology
BSC485/585 Viral Pathogenesis and Diagnosis
- Interleukin-17A signaling promotes CD8+ T cell cytotoxicity against West Nile virus infection through enhancing PI3K-mTOR-mediated metabolism , Plos Pathogens, 2025, https://doi.org/10.1371/journal.ppat.1013218
- Heterozygous Interferon Signaling Deficient Mice as Animal Models for Chikungunya Virus Infection in the Heart, Scientific Reports, 2025, https://www.nature.com/articles/s41598-025-02191-9
- A Comprehensive Review of the Neglected and Emerging Oropouche Virus, Viruses, 2025, https:// doi.org/10.3390/v17030439
- A novel nanocomposite drug delivery system for SARS-CoV-2 infections, Nanoscale ADV, 2024, 10.1039/d4na00361f.
- An effective live-attenuated Zika vaccine candidate with a modified 5' untranslated region, NPJ Vaccines, 2023, 10.1038/s41541-023-00650-w
- Book: West Nile virus - Methods and Protocols, 2023, https://link.springer.com/book/10.1007/978-1-0716-2760-0
- A Dual-Approach Strategy to Optimize the Safety and Efficacy of Anti-Zika Virus Monoclonal Antibody Therapeutics, Viruses, 2023, 10.3390/v15051156
- Mouse trophoblast cells can provide interferon-based antiviral protection to embryonic stem cells via paracrine signaling, Journal of Immunology, 2022, 10.4049/jimmunol.2100679
- Murine Trophoblast Stem Cells and Their Differentiated Cells Attenuate Zika Virus In Vitro by Reducing Glycosylation of the Viral Envelope Protein, Cells, 2021, 10.3390/cells10113085
- Interleukin-17A Facilitates Chikungunya Virus Infection by Inhibiting IFN-α2 Expression, Front Immunol., 2020, 10.3389/fimmu.2020.588382
- American Society of Microbiology
- American Heart Association
- The American Association of Immunologists
- English (Full Professional)
- Chinese (Native or Bilingual)