My lab investigatres the molecular mechanisms that underlie mast cell exocytosis. We are particularly interested in understanding how different mediators (e.g., histamine and TNF) are differentially released in various pathological conditions, including allergic reaction and pathogenic infection.
ELISA, confocal microscopy, cell culture, CRISPRE, RNAi, in vitro reconstitution, protein expression and purification, immunoprecipitation, molecular cloning
- Tolulope Ayo (graduate student)
- John Vine (graduate student)